From the APS Journal Archive: Genes for Psychosis and Creativity

‘Genes for Psychosis and Creativity’ by Szabolcs Kér1 was published in Psychological Science in September 2009 and has been cited 16 times (via Web of Science) since publication.

Click here to read the article in full.

Abstract:

Why are genetic polymorphisms related to severe mental disorders retained in the gene pool of a population? A possible answer is that these genetic variations may have a positive impact on psychological functions. Here, I show that a biologically relevant polymorphism of the promoter region of the neuregulin 1 gene (SNP8NRG243177/rs6994992) is associated with creativity in people with high intellectual and academic performance. Intriguingly, the highest creative achievements and creative-thinking scores were found in people who carried the T/T genotype, which was previously shown to be related to psychosis risk and altered prefrontal activation.

1Semmelweis University

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